SCience art

publications

Schorova, L; Bedard, N; Khayachi, A; Ho, HH; Bolivar-Pedroso, J; Huynh, J et al. Genetic inactivation of the USP19 deubiquitinase regulates α -synuclein ubiquitination and inhibits accumulation of Lewy body-like aggregates in mice. npj Parkinson's Disease (Nov 28 2023). https://www.nature.com/articles/s41531-023-00601-1

Tessier, A. J., S. S. Wing, E. Rahme, J. A. Morais, and S. Chevalier. "Physical Function-Derived Cut-Points for the Diagnosis of Sarcopenia and Dynapenia from the Canadian Longitudinal Study on Aging." J Cachexia Sarcopenia Muscle (Jul 15 2019). https://dx.doi.org/10.1002/jcsm.12462.

Coyne, E. S., N. Bedard, Y. J. Gong, M. Faraj, A. Tchernof, and S. S. Wing. "The Deubiquitinating Enzyme Usp19 Modulates Adipogenesis and Potentiates High-Fat-Diet-Induced Obesity and Glucose Intolerance in Mice." Diabetologia 62, no. 1 (Jan 2019): 136-46. https://dx.doi.org/10.1007/s00125-018-4754-4.

Coyne, E. S., N. Bedard, L. Wykes, C. Stretch, S. Jammoul, S. Li, K. Zhang, R. S. Sladek, O. F. Bathe, R. T. Jagoe, B. I. Posner, and S. S. Wing. "Knockout of Usp19 Deubiquitinating Enzyme Prevents Muscle Wasting by Modulating Insulin and Glucocorticoid Signaling." Endocrinology 159, no. 8 (Aug 1 2018): 2966-77. https://dx.doi.org/10.1210/en.2018-00290.

Hall, D. T., T. Griss, J. F. Ma, B. J. Sanchez, J. Sadek, A. M. K. Tremblay, S. Mubaid, A. Omer, R. J. Ford, N. Bedard, A. Pause, S. S. Wing, S. Di Marco, G. R. Steinberg, R. G. Jones, and I. E. Gallouzi. "The Ampk Agonist 5-Aminoimidazole-4-Carboxamide Ribonucleotide (Aicar), but Not Metformin, Prevents Inflammation-Associated Cachectic Muscle Wasting." EMBO Mol Med 10, no. 7 (Jul 2018). https://dx.doi.org/10.15252/emmm.201708307.

Tanaka, K. I., Y. Xue, L. Nguyen-Yamamoto, J. A. Morris, I. Kanazawa, T. Sugimoto, S. S. Wing, J. B. Richards, and D. Goltzman. "Fam210a Is a Novel Determinant of Bone and Muscle Structure and Strength." Proc Natl Acad Sci U S A 115, no. 16 (Apr 17 2018): E3759-e68. https://dx.doi.org/10.1073/pnas.1719089115.

Bose, R., K. Sheng, A. R. Moawad, G. Manku, C. O'Flaherty, T. Taketo, M. Culty, K. L. Fok, and S. S. Wing. "Ubiquitin Ligase Huwe1 Modulates Spermatogenesis by Regulating Spermatogonial Differentiation and Entry into Meiosis." Sci Rep 7, no. 1 (Dec 19 2017): 17759. https://dx.doi.org/10.1038/s41598-017-17902-0.

Fok, K. L., R. Bose, K. Sheng, C. W. Chang, M. Katz-Egorov, M. Culty, S. Su, M. Yang, Y. C. Ruan, H. C. Chan, A. Iavarone, A. Lasorella, R. Cencic, J. Pelletier, M. Nagano, W. Xu, and S. S. Wing. "Huwe1 Regulates the Establishment and Maintenance of Spermatogonia by Suppressing DNA Damage Response." Endocrinology 158, no. 11 (Nov 1 2017): 4000-16. https://dx.doi.org/10.1210/en.2017-00396.

Coyne, E. S. and S. S. Wing. "The Business of Deubiquitination - Location, Location, Location." F1000Res 5 (2016). https://dx.doi.org/10.12688/f1000research.7220.1.

Sareen-Khanna, K., J. Papillon, S. S. Wing, and A. V. Cybulsky. "Role of the Deubiquitinating Enzyme Ubiquitin-Specific Protease-14 in Proteostasis in Renal Cells." Am J Physiol Renal Physiol 311, no. 5 (Nov 1 2016): F1035-f46. https://dx.doi.org/10.1152/ajprenal.00252.2016.

Attaix, D. and S. S. Wing. "Proteolysis - a Master Regulator in Health and Disease." Int J Biochem Cell Biol 79 (Oct 2016): 402. https://dx.doi.org/10.1016/j.biocel.2016.09.001.

Wing, S. S. "Deubiquitinating Enzymes in Skeletal Muscle Atrophy-an Essential Role for Usp19." Int J Biochem Cell Biol 79 (Oct 2016): 462-68. https://dx.doi.org/10.1016/j.biocel.2016.07.028.

Bilodeau, P. A., E. S. Coyne, and S. S. Wing. "The Ubiquitin Proteasome System in Atrophying Skeletal Muscle: Roles and Regulation." Am J Physiol Cell Physiol 311, no. 3 (Sep 1 2016): C392-403. https://dx.doi.org/10.1152/ajpcell.00125.2016.

Bedard, N., S. Jammoul, T. Moore, L. Wykes, P. L. Hallauer, K. E. Hastings, C. Stretch, V. Baracos, S. Chevalier, M. Plourde, E. Coyne, and S. S. Wing. "Inactivation of the Ubiquitin-Specific Protease 19 Deubiquitinating Enzyme Protects against Muscle Wasting." Faseb j 29, no. 9 (Sep 2015): 3889-98. https://dx.doi.org/10.1096/fj.15-270579.

Wiles, B., M. Miao, E. Coyne, L. Larose, A. V. Cybulsky, and S. S. Wing. "Usp19 Deubiquitinating Enzyme Inhibits Muscle Cell Differentiation by Suppressing Unfolded-Protein Response Signaling." Mol Biol Cell 26, no. 5 (Mar 1 2015): 913-23. https://dx.doi.org/10.1091/mbc.E14-06-1129.

Yang, Y., D. Duguay, J. Fahrenkrug, N. Cermakian, and S. S. Wing. "Usp2 Regulates the Intracellular Localization of Per1 and Circadian Gene Expression." J Biol Rhythms 29, no. 4 (Aug 2014): 243-56. https://dx.doi.org/10.1177/0748730414544741.

Bose, R., G. Manku, M. Culty, and S. S. Wing. "Ubiquitin-Proteasome System in Spermatogenesis." Adv Exp Med Biol 759 (2014): 181-213. https://dx.doi.org/10.1007/978-1-4939-0817-2_9.

Stojkovic, K., S. S. Wing, and N. Cermakian. "A Central Role for Ubiquitination within a Circadian Clock Protein Modification Code." Front Mol Neurosci 7 (2014): 69. https://dx.doi.org/10.3389/fnmol.2014.00069.

Wing, S. S. "Deubiquitinases in Skeletal Muscle Atrophy." Int J Biochem Cell Biol 45, no. 10 (Oct 2013): 2130-5. https://dx.doi.org/10.1016/j.biocel.2013.05.002.

Manku, G., S. S. Wing, and M. Culty. "Expression of the Ubiquitin Proteasome System in Neonatal Rat Gonocytes and Spermatogonia: Role in Gonocyte Differentiation." Biol Reprod 87, no. 2 (Aug 2012): 44. https://dx.doi.org/10.1095/biolreprod.112.099143.

Yang, Y., D. Duguay, N. Bedard, A. Rachalski, G. Baquiran, C. H. Na, J. Fahrenkrug, K. F. Storch, J. Peng, S. S. Wing, and N. Cermakian. "Regulation of Behavioral Circadian Rhythms and Clock Protein Per1 by the Deubiquitinating Enzyme Usp2." Biol Open 1, no. 8 (Aug 15 2012): 789-801. https://dx.doi.org/10.1242/bio.20121990.

Older publications can be accessed via PubMed:

https://www.ncbi.nlm.nih.gov/pubmed/?term=Wing%20SS%5BAuthor%5D&cauthor=true&cauthor_uid=31307126